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Weinberg/Keiver酒精液體模型飼料
Weinberg/Keiver Ethanol Liquid Diet(TP4040)

一、Weinberg/Keiver ethanol liquid Diet介紹


Weinberg/Keiver酒精液體模型飼料
【1】Weinberg/Keiver酒精液體模型飼料:

脂肪16.4%,蛋白質25%,碳水化合物23.1%,酒精35.5%。

南通特洛菲飼料科技有限公司生產的該模型飼料的代碼:TP4040;

【2】Weinberg/Keiver酒精液體對照飼料:

脂肪16.4%, 蛋白質25%, 碳水化合物58.6%。

南通特洛菲飼料科技有限公司生產的該對照飼料的代碼:TP4040C;

Weinberg/Keiver酒精液體模型飼料是一種高蛋白型酒精液體造模飼料,專用于妊娠期和哺乳期大鼠或小鼠。該飼料是在Lieber-DeCarli酒精液體飼料(Regular型,標準型)基礎上提高蛋白質含量,降低脂肪含量,而酒精含量維持不變。

Lieber-DeCarli高蛋白型酒精液體飼料中也有一款高蛋白型酒精液體模型飼料,蛋白質含量也是25%,也是用于Weinberg/Keiver酒精液體模型飼料。Weinberg/Keiver酒精液體模型飼料與Lieber-DeCarli高蛋白型酒精液體飼料的區別在于脂肪含量不同,營養素更平衡。

二、Weinberg/Keiver ethanol liquid Diet的用途


Weinberg/Keiver酒精液體模型飼料的用途
廣泛應用于妊娠期和哺乳期:

(1)酒精對母體生理機能的作用;

(2)酒精對母體營養的作用;

(3)酒精對胚胎發育的作用及其機理;

(4)酒精對后代的發育以及成年后生理機能的影響;

(5)胎兒酒精(中毒)綜合癥(Fetal alcohol syndrome,簡稱FAS)或(fetal alcohol spectrum disorder,FASD)或(FASARD Fetal alcohol syndrome and related disorders,FASRD)發病機理的研究,或用于FAS或FASD造模進行治療或干預的研究;

(6)酒精對后來成癮的聯系。

請注意不同種系和品系的差異。

三、Weinberg/Keiver ethanol liquid Diet應用的注意點


1.購買飼料前:

(1)應當做好動物的準備,注意動物的品種和品系的選擇。

(2)如果用于妊娠期,應當準備好妊娠方法的流程準備。

2. 購買前、后應當向公司索取以下資料:

《液體飼料配制方法》

《酒精液體飼料喂養方法》

《怎樣根據研究的需要調整酒精的配比》

 

References:

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[5] Weinberg J. 1989. Prenatal ethanol exposure alters adrenocortical development of offspring. Alcohol Clin Exp Res 13: 73–83.

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[14] Zhang X, Lan N, Bach P, Nordstokke D, Yu W, Ellis L, Meadows GG, Weinberg J. Prenatal alcohol exposure alters the course and severity of adjuvant-induced arthritis in female rats. Brain Behav Immun. 2012 Mar;26(3):439-50.

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[16] Ward IL, Bennett AL, Ward OB, Hendricks SE, French JA. Androgen threshold to activate copulation differs in male rats prenatally exposed to alcohol, stress, or both factors. Horm Behav. 1999 Oct;36(2):129-40.

[17] Ward IL, Ward OB, French JA, Hendricks SE, Mehan D, Winn RJ. Prenatal alcohol and stress interact to attenuate ejaculatory behavior, but not serum testosterone or LH in adult male rats. Behav Neurosci. 1996 Dec;110(6):1469-77.

[18] Ward OB, Ward IL, Denning JH, Hendricks SE, French JA. Hormonal mechanisms underlying aberrant sexual differentiation in male rats prenatally exposed to alcohol, stress, or both. Arch Sex Behav. 2002 Feb;31(1):9-16.

[19] Ward IL, Ward OB, Winn RJ, Bielawski D. Male and female sexual behavior potential of male rats prenatally exposed to the influence of alcohol, stress, or both factors. Behav Neurosci. 1994 Dec;108(6):1188-95.

[20] Ward IL, Romeo RD, Denning JH, Ward OB.Fetal alcohol exposure blocks full masculinization of the dorsolateral nucleus in rat spinal cord. Physiol Behav. 1999 Jun;66(4):571-5.

[21] Ward OB, Ward IL, Denning JH, French JA, Hendricks SE.Postparturitional testosterone surge in male offspring of rats stressed and/or fed ethanol during late pregnancy.Horm Behav. 2002 Mar;41(2):229-35.

[22] Uban KA, Sliwowska JH, Lieblich S, Ellis LA, Yu WK, Weinberg J, Galea LA. Prenatal alcohol exposure reduces the proportion of newly produced neurons and glia in the dentate gyrus of the hippocampus in female rats.Horm Behav. 2010 Nov;58(5):835-43.

[23] Sliwowska JH, Barker JM, Barha CK, Lan N, Weinberg J, Galea LA. Stress-induced suppression of hippocampal neurogenesis in adult male rats is altered by prenatal ethanol exposure.Stress. 2010 Jul;13(4):301-13.

[24] Sadrian B, Wilson DA, Saito M. Long-lasting neural circuit dysfunction following developmental ethanol exposure. Brain Sci. 2013 Apr 29;3(2):704-727.

[25] Redila VA, Olson AK, Swann SE, Mohades G, Webber AJ, Weinberg J, Christie BR. Hippocampal cell proliferation is reduced following prenatal ethanol exposure but can be rescued with voluntary exercise. Hippocampus. 2006;16(3):305-11.

[27] McGivern RF, Ervin MG, McGeary J, Somes C, Handa RJ. Prenatal ethanol exposure induces a sexually dimorphic effect on daily water consumption in prepubertal and adult rats. Alcohol Clin Exp Res. 1998 Jun;22(4):868-75.

[28] McGivern RF, Handa RJ, Raum WJ. Ethanol exposure during the last week of gestation in the rat: inhibition of the prenatal testosterone surge in males without long-term alterations in sex behavior. Neurotoxicol Teratol. 1998 Jul-Aug;20(4):483-90.

[29] Aird F, Halasz I, Redei E. Ontogeny of hypothalamic corticotropin-releasing factor and anterior pituitary pro-opiomelanocortin expression in male and female offspring of alcohol-exposed and adrenalectomized dams. Alcohol Clin Exp Res. 1997 Dec;21(9):1560-6.

[30] Wilson ME, Handa RJ.Gonadotropin secretion in infantile rats exposed to ethanol in utero.Alcohol. 1997 Sep-Oct;14(5):497-501.

[31] Handa RJ, Zuloaga DG, McGivern RF. Prenatal ethanol exposure alters core body temperature and corticosterone rhythms in adult male rats. Alcohol. 2007 Dec;41(8):567-75.

[32] Allen GC, Farnell YZ, Maeng JU, West JR, Chen WJ, Earnest DJ. Long-term effects of neonatal alcohol exposure on photic reentrainment and phase-shifting responses of the activity rhythm in adult rats. Alcohol. 2005 Oct;37(2):79-88.

[33] Glavas MM, Ellis L, Yu WK, Weinberg J. Effects of prenatal ethanol exposure on basal limbic-hypothalamic-pituitary-adrenal regulation: role of corticosterone. Alcohol Clin Exp Res. 2007 Sep;31(9):1598-610.

[34] Farnell YZ, Allen GC, Neuendorff N, West JR, Wei-Jung AC, Earnest DJ. Effects of neonatal alcohol exposure on vasoactive intestinal polypeptide neurons in the rat suprachiasmatic nucleus. Alcohol. 2009 Aug;43(5):387-96.

[35] Osborn JA, Yu C, Stelzl GE, Weinberg J. Effects of fetal ethanol exposure on pituitary-adrenal sensitivity to secretagogues. Alcohol Clin Exp Res. 2000 Jul;24(7):1110-9.

[36] Hofmann CE, Ellis L, Yu WK, Weinberg J. Hypothalamic-pituitary-adrenal responses to 5-HT1A and 5-HT2A/C agonists are differentially altered in female and male rats prenatally exposed to ethanol. Alcohol Clin Exp Res. 2007 Feb;31(2):345-55.

[37] Glavas MM, Yu WK, Weinberg J. Effects of mineralocorticoid and glucocorticoid receptor blockade on hypothalamic-pituitary-adrenal function in female rats prenatally exposed to ethanol. Alcohol Clin Exp Res. 2006 Nov;30(11):1916-24.

[38] McGivern RF, Handa RJ, Redei E. Decreased postnatal testosterone surge in male rats exposed to ethanol during the last week of gestation. Alcohol Clin Exp Res. 1993 Dec;17(6):1215-22.

[39] McGivern RF, Handa RJ, Raum WJ. Ethanol exposure during the last week of gestation in the rat: inhibition of the prenatal testosterone surge in males without long-term alterations in sex behavior. Neurotoxicol Teratol. 1998 Jul-Aug;20(4):483-90.

[40] Ward IL, Ward OB, Affuso JD, Long WD 3rd, French JA, Hendricks SE. Fetal testosterone surge: specific modulations induced in male rats by maternal stress and/or alcohol consumption. Horm Behav. 2003 May;43(5):531-9.

[41] Rout UK, Dhossche JM. Liquid-diet with alcohol alters maternal, fetal and placental weights and the expression of molecules involved in integrin signaling in the fetal cerebral cortex. Int J Environ Res Public Health. 2010 Nov;7(11):4023-36.

[42] Weinberg J. Effects of ethanol and maternal nutritional status on fetal development. Alcohol Clin Exp Res 1985,9: 49–55.

[43] Taylor AN, Tritt SH, Tio DL, Romeo HE, Yirmiya R. Maternal adrenalectomy abrogates the effect of fetal alcohol exposure on the interleukin-1beta-induced febrile response: gender differences. Neuroendocrinology. 2002 Sep;76(3):185-92.

[44] Caldeira JC, Wu Y, Mameli M, Purdy RH, Li PK, Akwa Y, Savage DD, Engen JR, Valenzuela CF. Fetal alcohol exposure alters neurosteroid levels in the developing rat brain. J Neurochem. 2004 Sep;90(6):1530-9.

[45] Aird F, Halasz I, Redei E. Ontogeny of hypothalamic corticotropin-releasing factor and anterior pituitary pro-opiomelanocortin expression in male and female offspring of alcohol-exposed and adrenalectomized dams.Alcohol Clin Exp Res. 1997 Dec;21(9):1560-6.



有困惑?那就商量唄!

液體飼料的優點,你可以充分運用!

---------《》-------

marker可以任意缺乏或過載某營養素

marker可以任意添加藥物或測試成分

marker可以精確定量飼料攝入量

marker可以任意定制飼料


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